DPCstruct | MC45395

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)135 ± 11 aa
Standard deviation of domain lengths11.12
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.32
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)27.95
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I2YQB5 1-135 MTTNRQVQKNLADLRSRIIRGEIGKTILWQGADVVILAELPGESEPGFYPDPLFVRSDFAEELSWLFYELKAAFDDQIDFENKFYFY…
A0A418PRI7 2-113 KEQLQTLREKINSGQFPTHFPHFGGANLIITDNPNRSFHEGDVVIYTAHASAMSWLVMELKEIYGGHLNSLSKYRFYPEIGKLIQES…
A0A7V0YGX7 1-147 None
A0A7I7PKQ4 193-332 None
A0A2T1E009 7-148 None
I5C8F0 1-124 None
A0A7X7I480 153-298 None
A0A419GLS7 14-148 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.