DPCstruct | MC45369

Metacluster Properties and Pfam Annotations

Number of structural domains272
Mean domain length (aa)134 ± 21 aa
Standard deviation of domain lengths21.27
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.52
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)15.75
Pfam Score98.50
Assigned Pfam label(s) PF07896- PF03016- PF01288- CL0334

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V3GT60 20-160 ISNHFSRKRNILFKTGVPMFTLALRKKFIAHHHAASEIDADHPMRSHLYILEVMLEAEELDSEGYVLDLDELEAEVDDILSQYAYKS…
A0A1X1EX88 1-118 MSTTLFKEFQFEAAHRLPHVPEGHKCGRLHGHSFLVRLEITGEVDAYTGWVMDFAELKAAFAPIYDRLDHHYLNDIPGLSNPTSEVL…
A0A6S8B586 8-195 None
A0A7C5VEH8 78-230 None
A0A7W5S3D5 2-97 None
B9EM09 60-204 None
M1V5S6 46-204 None
A0A497I5S0 2-106 None
A0A7U6QJ76 2-117 None
R5G886 354-484 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.