DPCstruct | MC45324

Metacluster Properties and Pfam Annotations

Number of structural domains408
Mean domain length (aa)399 ± 107 aa
Standard deviation of domain lengths107.34
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score85.66
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.67
Pfam Score82.51
Assigned Pfam label(s) PF05199- CL0063- CL0559- PF00172- PF00696

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0W0EVZ1 135-664 None
A0A376L1G5 1-235 None
M6BKL3 3-294 None
A0A1Q7YD65 199-705 None
A0A7S8ICT3 530-1008 None
A0A423TIA0 132-472 None
A0A159Z9N1 3-215 None
A0A1I7H746 8-335 None
A0A7S3EYW9 3-248 None
A0A3A3A5N3 559-1066 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.