DPCstruct | MC45324

Metacluster Properties and Pfam Annotations

Number of structural domains408
Mean domain length (aa)399 ± 107 aa
Standard deviation of domain lengths107.34
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score85.66
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.67
Pfam Score82.51
Assigned Pfam label(s) PF05199- CL0063- CL0559- PF00172- PF00696

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2M425 85-436 None
A0A2P8YJ20 301-752 None
A0A395J7F0 20-444 None
A0A395IND2 12-251 None
A0A6P3Z105 58-422 None
A0A0C3ERH0 21-461 None
A0A2E0DM50 12-296 None
A0A109LIT2 2-262 None
Q025P1 41-513 None
A0A094FNW3 32-467 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.