DPCstruct | MC45324

Metacluster Properties and Pfam Annotations

Number of structural domains408
Mean domain length (aa)399 ± 107 aa
Standard deviation of domain lengths107.34
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score85.66
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)17.67
Pfam Score82.51
Assigned Pfam label(s) PF05199- CL0063- CL0559- PF00172- PF00696

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J2YFW4 50-414 None
A0A409XNF4 56-289 None
A0A1I7EGC0 2-219 None
A0A4V2SNP5 342-820 None
A0A0L7KB12 35-375 None
A0A5B8Y0C2 284-751 None
A0A131YSQ1 47-467 None
A0A6G0TMA7 125-610 None
A0A426VMD6 122-481 None
A0A4R9DXK6 2-209 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.