DPCstruct | MC45280

Metacluster Properties and Pfam Annotations

Number of structural domains167
Mean domain length (aa)169 ± 31 aa
Standard deviation of domain lengths30.97
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score75.31
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)19.98
Pfam Score97.32
Assigned Pfam label(s) CL0229- CL0103- PF02466

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5K4FA16 145-306 DMDEFSRDPCPFRIVSDCGAAFAMGTIGGSVLHFYRGYRNAPSGYTKKLVSAMVNSRQRAPITGGGFAIWGGVFTAVDCSLVLARRK…
A0A814JLN6 5-144 PCPWRIVDDCGGAFALGTIGGSLFHSIKGFRHAPSGQYRRLLGSLNAVKQRAPRVGASFSAWGAIFSTVDCSFVYLRKKEDPWNSIM…
F4PWV3 1-173 None
A0A444WWV7 33-149 None
A0A5N6Q4Y1 268-427 None
G0P2Y5 396-553 None
J4UHP8 51-234 None
C4JSP3 160-307 None
A0A5N6P4N9 893-1128 None
A0A1E5UY50 115-330 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.