DPCstruct | MC4527

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)241 ± 17 aa
Standard deviation of domain lengths17.06
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score88.56
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)39.94
Pfam Score100.00
Assigned Pfam label(s) PF10720

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A845EM32 1-211 KDNISRTKAYFNYYVAHPEIKWSFLASMVSRNAGYNMTDLWLSPFTNMLNKRERSRMFMTYERANWLIFSDAYPQLLTYELSIYQNK…
S4Y6D5 18-249 LTALLDELDARNVDNVARTESYLELYALTRAHPPDLPWLLMAHLVSRNAGALMTEIAAALDRREGAIAPSALRESFLFLERANHLIF…
W4QTU3 72-303 None
A0A268E4W6 2-232 None
A0A0C2R9V2 33-295 None
A0A516KHP8 56-318 None
A0A653UXK5 20-274 None
D8H7G2 47-285 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.