DPCstruct | MC45244

Metacluster Properties and Pfam Annotations

Number of structural domains210
Mean domain length (aa)202 ± 50 aa
Standard deviation of domain lengths50.24
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score84.40
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)22.33
Pfam Score98.64
Assigned Pfam label(s) PF01765- PF01101- CL0061- PF01255

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A426H4U2 11-213 KLPKHIAIIMDGNGRWAKEKGKLRVFGHKNGVVAVRDTVEGAAELGIENLTLYAFSTENWNRPKLEVTALMELLVATINKETKTLMD…
A0A6J3JQU2 3-155 LARQKFSRLMEEQEKLQKHGVCIRVLGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSD…
A0A534K804 109-312 None
A0A6G3VKJ1 5-123 None
A0A7V9V9N3 4-109 None
A0A1S8VIZ3 19-136 None
A0A1S8W379 153-333 None
A0A1Y2HK49 143-401 None
A0A6B2CDV5 3-222 None
M1V3U0 4-275 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.