DPCstruct | MC4518

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)228 ± 33 aa
Standard deviation of domain lengths32.97
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score82.31
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)26.52
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3HC53 23-239 CQHGDRRGTVFINDTRTCRDFQTAQVTWHCYSQVARGYCCDSCSDVYNASDTGCLYGDKAPFCINITRRQCYGKTNQNEPVPDVCCR…
A0A3S1HIR9 54-279 HPRDSCPQGDQPGVVHDGKTCEDIVRLTPWACYDDFYRRKCCISCPGISKEATDCPYGDRESWCQTDKMNYPYDCYLNNATCCQSCA…
T1ETK8 292-547 None
R7UPS0 40-235 None
A0A2C9KE57 2-218 None
T1FHV2 306-529 None
T1FPL5 229-450 None
A0A8B6BS24 235-493 None
V4AHG6 500-704 None
V4BB17 388-551 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.