DPCstruct | MC45172

Metacluster Properties and Pfam Annotations

Number of structural domains116
Mean domain length (aa)150 ± 25 aa
Standard deviation of domain lengths24.72
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.86
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)26.31
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M1WG97 82-217 FDYDPHSKVWDEFNRLAKNFHWQEGSQKEKKARNLFRQALVDEFGANYGESDSKLDVLQRLCQKLEIGPMPQSITACKKAINSVYVN…
A0A8A3PF00 8-108 IAADFDRYFGNQSVLANWQRLCHDVRIEGADGLRSIRACREALSKVHVNIYELVDANLAGTPVRLFATRAELIRWTVSHKRYFPLKK…
A0A0S6XC81 13-143 None
A0A317AZF7 442-642 None
A0A0J6FPD9 22-162 None
A0A1V6S3G0 6-145 None
A0A4S2MKJ0 128-298 None
A0A1J9QM46 157-330 None
A0A3N4I7M8 58-253 None
A0A4U0V7F7 58-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.