DPCstruct | MC45139

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)475 ± 75 aa
Standard deviation of domain lengths75.33
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.19
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.30
Pfam Score100.00
Assigned Pfam label(s) CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J4EEA5 7-449 ENQERIVIPAIIGCFFILIMICLTDIIPFSVVNEDINNARGILGGVGVEGLSAIFAIVISLTLMAVQFASQEYTHRIMDIHIKSLIF…
A0A849QYX2 9-366 YKWMKYKYWIYCIIPTLVVFLILYCAPPDECPENARYILSAISQSLAAILALVFTITLVIAQMTKRYMAMDEIIFRLETKLLMSLFG…
A0A1X7E7Y0 13-564 None
A0A4Q3PNZ5 39-503 None
A0A7C1E4Y6 140-570 None
A0A017HSP4 121-595 None
A0A3A5BD60 1-432 None
A0A4P7RH00 242-760 None
A0A447G186 34-536 None
A0A7S2W664 281-839 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.