DPCstruct | MC4505

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)77 ± 4 aa
Standard deviation of domain lengths3.88
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score87.61
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)29.46
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q8CYT5 1-85 MNCRGHETRQRIVRDFEVQPKVHIKLLANQQKHSDAGATIEDEYYVFIAESKIDGKKEVIQCCMGAARDFLELINHKGLPLFNPL
A0A348DK76 3-83 WPKEYSKTTQAVRDAAFKLYYVEAITQSVLLPGQVKTAYHGGPLTTGYYLFLFTSRENPKLTGYFTCGLYAAKGWFEVNGQ
A0A174H491 16-94 None
A0A1C6GDB1 1-79 None
A0A5P2EZT5 7-82 None
A0A1T1DCJ1 1-77 None
A0A2A2M7Z0 11-88 None
A0A2M9Q9Y2 5-76 None
A0A546X903 6-77 None
A0A7X4ZRE7 1-72 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.