DPCstruct | MC4503

Metacluster Properties and Pfam Annotations

Number of structural domains70
Mean domain length (aa)133 ± 25 aa
Standard deviation of domain lengths25.31
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score68.79
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)30.90
Pfam Score98.81
Assigned Pfam label(s) CL0220- PF02187

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A820RF93 1-90 ADIDRIKSEVHRQTSLCQCSNKYDVQQIAEGRYRFGGSQSLRLVRILRSTVMVRVGGGWTALDEFLVRHDPCRGNRKKRAIYRTTAF…
A0A2G8KVN5 24-134 KNPRPPSGKSKKTIGKLDKEVQCIAKVCKVDVHRVSEGRYNILGKLVFVRMLRGRHVMVRVGGGWDTLEHYLIRHEPTSFRLHSRNM…
A0A7S1MDH3 481-621 None
A0A3P6HVG3 92-216 None
A0A6J0J3Y9 155-311 None
A0A7J6D2R4 423-562 None
A0A834XUQ4 227-349 None
B4DWX4 7-124 None
T1EF51 38-199 None
A0A1I8IRY1 26-115 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.