DPCstruct | MC4501

Metacluster Properties and Pfam Annotations

Number of structural domains146
Mean domain length (aa)193 ± 47 aa
Standard deviation of domain lengths47.43
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score81.40
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.53
Pfam Score98.08
Assigned Pfam label(s) CL0137- CL0124- PF00110- CL0065- CL0158

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A674HSY6 589-796 LPRDWLWGGCGDNVEYGYRFAKEFVDAKEREKNYVRGSEEQARMLMNLQNNEAGRRAVYKLADVACKCHGVSGSCSLKTCWLQLADF…
A0A2G8KSN9 64-258 DTVEVDSDANSLMNLHNNEAGRKAVRSTLEKRCKCHGVSGSCTLQTCWTQLSDFSTIGRFLRKKYLTASQVDLSRGHLTQSNDFMEV…
A0A3P7CV01 1-211 None
A0A2T7PZY9 195-422 None
A0A1Y3BGE3 1-164 None
A0A556TK44 790-996 None
A0A218VE97 266-379 None
A0A6P4L3Y6 246-412 None
A0A139WF66 371-574 None
A0A182F0Y5 82-350 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.