DPCstruct | MC44994

Metacluster Properties and Pfam Annotations

Number of structural domains101
Mean domain length (aa)127 ± 26 aa
Standard deviation of domain lengths26.24
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score76.97
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)18.06
Pfam Score49.30
Assigned Pfam label(s) PF09696- CL0662

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B5VKB9 64-196 MPSVDIDASQWQKLTQSREKQTTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKK…
A0A445CZA6 11-123 EDKEEGRCKEWAIVELQGVVEPQPGFHDSLPNLQIGTLCRPSSQEVYTLTIGYHELTGSKVPLKKPMMVLKKVKHSPLDRGESSGCG…
A0A059AW81 51-146 None
A0A6U3NRN2 3-133 None
Q5BBV3 202-342 None
A0A813BIW9 159-262 None
A0A4S8MQ45 24-169 None
A0A4Y7JCE6 239-371 None
A0A7S2UGU6 54-186 None
A0A016U7X0 1-81 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.