DPCstruct | MC44980

Metacluster Properties and Pfam Annotations

Number of structural domains215
Mean domain length (aa)124 ± 33 aa
Standard deviation of domain lengths33.31
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score87.94
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)29.34
Pfam Score98.35
Assigned Pfam label(s) CL0260- PF04381- CL0063- CL0236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5D8MYJ5 15-109 IPKELITSGFSSCYSRLDRDEPAVTITVNFVHPASNRCIHPILNRALTPREGARLQSFDDDFKFFGNRSEITKQIGNAVPPLLGKAI…
A0A239R377 109-215 GPYDKKFMARNRVRGWDELSFTIQAQAKNEPLHPQAPKMVYVSPQERQFVKGKECLYRRLSVRECARIQTFPDSFKFVYDKVIDGYK…
A0A350PGB6 62-131 None
A0A139PNE9 112-246 None
A0A4V3SIJ0 771-919 None
A0A167MDK8 2-85 None
A0A437S9J0 563-693 None
R9NZM2 399-592 None
A0A4Q1EV43 84-178 None
G2YS91 616-763 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.