DPCstruct | MC44977

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)81 ± 8 aa
Standard deviation of domain lengths8.32
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score82.71
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)35.64
Pfam Score100.00
Assigned Pfam label(s) CL0374

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V7KJP3 72-144 DNTREYDRTGLDQQRTELLDVELPLVTVPLNPGKNLTVICEVVAMNHLLRYSGVDSANAFNERLIRRMREKGG
A0A7J4V9Z3 9-83 DPGVEYTRTGLDTDSTTIMEVDLPYIRLPIVPGKNITVITEVIALNYLLKHYGYDSAKVFRERLERKLRQADGEN
A0A7V9Q4E2 115-200 None
A0A645HSR9 29-108 None
A0A7W1E8F0 50-141 None
A0A1V6HZU7 136-236 None
A0A1S9D3E9 255-337 None
A0A6L5DCX7 616-696 None
A0A7V2Z224 282-361 None
A0A7C4SYJ1 1-64 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.