DPCstruct | MC44973

Metacluster Properties and Pfam Annotations

Number of structural domains450
Mean domain length (aa)75 ± 15 aa
Standard deviation of domain lengths15.47
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.89
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)26.99
Pfam Score85.92
Assigned Pfam label(s) PF01556- PF00684

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5R9PN30 9-83 CQDCNGAGQKRCQDCNGSGNETLRCEVCDGKGYSFEKNDSGEYVQIICTNCNGSGEVSKTCRACNGTGNFICPTC
A0A0F9LVF1 11-57 SCPECDGIGEVVCDACGGKGGDCEHCKGLGHRVCRPCDGSGACPRCK
A0A7R9UFV6 97-169 None
A0A819NIU7 39-124 None
T1NPD1 197-266 None
A0A7S2SS88 135-199 None
A0A0C2J3N5 2-69 None
A0A2D6PPF5 172-276 None
A0A3D8IF31 142-207 None
A0A1Y4H7B3 88-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.