DPCstruct | MC44946

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)262 ± 36 aa
Standard deviation of domain lengths35.58
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score88.62
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)14.60
Pfam Score100.00
Assigned Pfam label(s) PF18928

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H0RC34 133-399 ISLSELIRTSLIEQKQKSIVKDAYQELFDINEKLRQLVDKETRYERDAKDIKGLFLSFSLAKAYKSHASIVNLCKLGFGEDGAIISR…
A0A1J5SMQ8 8-299 QQQKDLQEISELVHSFSSLGMDVIEHLLNASKIEKNKLASFFLFRQILEMGDAISVLINVGCINSCKPLIRSLIEYYFQLAYLLNEN…
A0A1M6M8Q2 32-346 None
A0A4Z0R3C9 41-305 None
A0A847D105 146-447 None
A0A7R9N8M3 2-247 None
A0A1G5WZ04 15-276 None
A0A2E0LAK5 89-416 None
A0A7K2AW77 18-258 None
A0A7T7YZ11 315-652 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.