DPCstruct | MC44916

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)348 ± 57 aa
Standard deviation of domain lengths57.14
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score89.33
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)33.52
Pfam Score95.34
Assigned Pfam label(s) CL0039- PF20979

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812IRJ5 279-642 VTFTADIGQGEEVEPARAKAKAMGVKEIFIEDLTEDFVANYVYPMFRANTVYEGEYLLGTSIARPLITRRLVEIARQTGAQAVAHGA…
A0A7U8U615 2-343 DVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNNALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVG…
A0A2B4S7F2 24-409 None
A0A667I390 297-585 None
A0A4T0HEV2 27-413 None
A0A5Q3DQG5 9-416 None
A0A6L5C892 311-648 None
A0A7V1K436 2-291 None
A0A7R9KWP3 7-359 None
A0A0R0IGZ2 2-244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.