DPCstruct | MC4490

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)141 ± 40 aa
Standard deviation of domain lengths40.06
Length coefficient of variation0.28
Mean AlphaFold2 pLDDT confidence score77.63
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)36.98
Pfam Score69.23
Assigned Pfam label(s) PF16165- CL0154

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0S7GW93 68-182 IPPRLTMQVWDADHFSADDFLGAIELDLNRFPRGAKTAKLCNLDMIRNEQELPTISIFKQKRVKGWWPFVARDENDEMELTGKVEAE…
A0A2G8KFV1 1-110 MTILAYLTCSCTLDLNRFPRGAKTSKKCTPDILKMDGTVPLMNLFKLKRHKGWWPFMAQSEHEEEELTGKVEAEMHLMTEEEAEKSP…
A0A0R3QTY1 163-319 None
F1L327 114-269 None
A0A6A5FIR9 595-823 None
A0A7J7KR59 75-193 None
A0A6P9AXB8 258-462 None
A0A7J7IXB1 281-407 None
T1K6Z8 166-281 None
A0A819I627 2-108 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.