DPCstruct | MC44872

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)95 ± 14 aa
Standard deviation of domain lengths13.73
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score82.52
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)30.27
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A395HPL5 221-303 YMGMFRHWLTVALDICDFSLPSETITTVYGDILLDRKFSGKVFLQGVLLPETKLGRGKFTYGYNLQHATVSGNRRSFSSPQEE
G2YV83 1-105 MGRGRGNKAASITKAEVMEWLKVCIHFDRPKEIVRTSCGNLILDSNFRGKVYLKGLFLEKTSRTRVIKYGYDFAQGHIGRDRKGMED…
A0A370PHC4 257-356 None
A0A0U5GP37 4-98 None
A0A6M7YU40 451-551 None
L2FWQ8 162-259 None
A0A319DKD5 3-90 None
Q2TX54 2-76 None
A0A7S4M0X7 1-99 None
A0A6A5UDA5 216-298 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.