DPCstruct | MC44869

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)130 ± 10 aa
Standard deviation of domain lengths9.77
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score90.34
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)42.05
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G2YIS9 1-118 MGSQWHTIKPYTAAVAPVWVALSPDDVLDNMDGAASKWGSATDASGKERVIRTEVPGWGWEGKTPKTIDTGERRKGRQRNAEPLTRE…
A0A1S8BG86 188-308 MLAAYISRWLGSPWHPTRPYPAAVAPVWLALASQELLDDAEELEGKGKWGSSTDRAGNERVSRTEVEGWGWGGIVGEATNRKGRRRG…
M2NF21 789-912 None
A0A366Q1B3 151-281 None
A0A0F8WRL9 1-149 None
U7PZA6 350-497 None
A0A0D2XQE0 81-211 None
T5ACF5 59-189 None
W9XMX8 276-398 None
A0A2J5HVM1 199-330 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.