DPCstruct | MC44860

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)142 ± 19 aa
Standard deviation of domain lengths18.87
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score89.37
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)73.73
Pfam Score96.88
Assigned Pfam label(s) PF00223- PF00421

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G3D3G0 1-135 MDNGDGIVVAWLGHPIFRDKEGRGLFVRRMPTFFETYPVILVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGKLNGVSYSDPAI…
A0A6A4N2W3 188-338 MDSGDGIAVGWLGHPIFKDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVGYNDPAT…
A0A7J9KP56 113-206 None
A0A830C908 93-260 None
A0A814RG48 330-480 None
A0A2R4QHC3 292-426 None
A0A1S4AEF0 41-192 None
B9SD21 119-266 None
A0A650F2R9 100-250 None
A0A453N3H7 1-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.