DPCstruct | MC44858

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)127 ± 14 aa
Standard deviation of domain lengths14.32
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score91.39
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)44.53
Pfam Score79.09
Assigned Pfam label(s) CL0344- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7I0KLZ0 4-115 LAYGARAITEGGYQSVPRLSFAGGVLIGCAAGFVNVPRIKGVHNAMGSAMLAAEHVNAALAAGRANDELVDYENAWRSSPVGEDLFK…
A0A2G3CUE3 1-110 MLAAESAFSMLQKGLKMENYWDNLRSSWIWEELYTARNYRPAFEYGLYPGLALSAVEHYILKGRSPVTLNHGKPDHEATRGEHDWHH…
A0A7F8QQW2 320-464 None
A0A7J6S2S0 673-799 None
A0A0V0J8P4 62-183 None
A0A7W8H2J0 172-313 None
A0A446JW70 2-108 None
F4Q8G1 971-1114 None
A0A855HMG5 1-137 None
A0A2A2K9F3 20-128 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.