DPCstruct | MC44844

Metacluster Properties and Pfam Annotations

Number of structural domains538
Mean domain length (aa)279 ± 74 aa
Standard deviation of domain lengths74.11
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score89.10
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)17.74
Pfam Score72.61
Assigned Pfam label(s) PF02770- CL0087- CL0304- CL0015- PF11794

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C9SF65 24-342 None
A0A7W4C9X8 114-316 None
A0A2D5WSM5 3-188 None
A0A535EI02 2-158 None
A0A535EGN7 45-332 None
A0A5N5WNF4 8-203 None
A0A7G1I9B3 2-173 None
A0A7G1I6X7 10-217 None
A0A1V4QKH5 26-241 None
A0A128ESS1 45-395 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.