DPCstruct | MC44841

Metacluster Properties and Pfam Annotations

Number of structural domains589
Mean domain length (aa)210 ± 34 aa
Standard deviation of domain lengths33.61
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.49
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)13.23
Pfam Score42.39
Assigned Pfam label(s) CL0123- PF08708- PF16793- CL0243- PF08800

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A662QZL8 156-341 SISKFLSFLVRGNFYWETRFIREKVISDKFHSNIIEIFEHLSKFRLNEADFYIGINPRSEKIRKKEGVKFGNVIFVDFDSEMARNDI…
A0A354C5H6 8-232 KTFTLFDSEVWKFFFNPGEVTEVRIPKVLNRGTVSGYFDDHEIFCKEVKKADKELNHDGIYFTLQVIDPRLLARAFNRLKVSSLTTS…
A0A7T5JUD8 100-328 None
A0A847SNH6 153-403 None
A0A4Y3K783 5-142 None
A0A4R5MCJ8 26-225 None
A0A6G6YMQ7 20-207 None
A0A6G1LY60 97-281 None
A0A146HC71 163-360 None
A0A2A2YA74 109-314 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.