DPCstruct | MC448

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)160 ± 20 aa
Standard deviation of domain lengths20.22
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score71.61
Mean fraction of residues predicted as intrinsically disordered0.83
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)28.68
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S5AXT0 1-134 MQREPDDHDATWRSIVENYGDPVLEPDEELAPQVEPAAPAWNPDDDSDRIPAELDDTFVPPPAPPIPRPSSDRLLAWLGLFGAPAIL…
A0A1H8IPF7 1-158 MADREDEGAAPLDEDAAWAALIAGFDEEPAPGAKSAWPDAENVAEEPPVPKAPPPARSIVVHPVIQGPRDYELEDDDEDAHFVPPEP…
A0A0A0J6P6 2-127 None
A0A4T0UQG8 251-415 None
A0A354XP04 9-143 None
A0A6I5X4S2 2-160 None
A0A4Y3R698 20-220 None
A0A0S9QA94 5-172 None
A0A1J7C9D9 21-181 None
A0A6V8LEL7 3-139 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.