DPCstruct | MC4478

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)228 ± 18 aa
Standard deviation of domain lengths18.15
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score81.60
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)21.97
Pfam Score100.00
Assigned Pfam label(s) PF04121

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1W4V766 2-235 MRTYLACNKMDCVRQTFRMVPGDIVPQIVGIYGSVDNIPPREECCLKEYLCYKVYLTGVDSFVEWNRLQLNRPKKPQAGMSVSAQDN…
A0A1I8AZM3 2-244 LRAWKWLTFCGTELIWDAIVEANYLLRKFFLHNRMDEAMELMRMAPESLGADYFQEKFPDVEVPIRLLDAKYEFECYQFYFEAINRY…
A0A0L0C1X8 607-872 None
A0A7S0G058 210-417 None
A0A7R8WN62 7-214 None
A0A183BHN2 542-773 None
A0A0B2V804 102-305 None
A0A2S2PJQ5 20-243 None
A0A1D2MFK1 631-873 None
H3DPY3 199-409 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.