DPCstruct | MC4476

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)66 ± 7 aa
Standard deviation of domain lengths6.94
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score79.63
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)74.64
Pfam Score94.12
Assigned Pfam label(s) CL0123- CL0062- PF03345

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5B7FNW2 1-59 MSPSVAKKTRKSLTLKVKLDIIHRHKRGQKTNSIACHHGLTPSTVSTIFKSADFIKKAG
A0A5B7H8X8 33-100 MPPKCPATRLAMSPSIAKKTRKSLTHEVKLDIIDGHVRGEKTNSIARHHGLTPSTVSIFKSADSIKKA
A0A5B7IP28 1-58 None
A0A5B7J6Y0 58-116 None
A0A5B7DLK5 370-438 None
A0A5B7DCG5 1-79 None
A0A5B7F7F3 25-90 None
A0A5B7FGW7 108-177 None
A0A5B7F7Z3 1-65 None
A0A5B7F1P7 2-74 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.