DPCstruct | MC4474

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)211 ± 17 aa
Standard deviation of domain lengths16.51
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score85.07
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)34.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5B7H4M2 3-218 MRLCETESQALKANLGHLLSPEVSSSLMWFLRRFCLSYLSPDESFYTEASSFCSIPLSSSSLPHPLSVALTSAFGRDSEGAAWTLNY…
H2ZC65 446-645 VLRVSEIETESLKTGMIGLLSPQLSEDILWFLRIWAATYLLYKEEYYKELSPVLSCAFGRDSDGSKWLIRHLVIKIMTSLTHWGSET…
A0A6B0R096 363-563 None
A0A287F9C0 227-467 None
S9X9K1 199-420 None
A0A2P2MR29 182-386 None
A0A6A3B9Q1 28-237 None
A0A7R9CKL7 2-202 None
A0A452YFL0 26-236 None
A0A452YFI7 117-358 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.