DPCstruct | MC4473

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)107 ± 16 aa
Standard deviation of domain lengths15.71
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score89.55
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)49.56
Pfam Score100.00
Assigned Pfam label(s) PF02898

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W4Q223 138-230 DTTRDSTLWKDRALVELNAAVLHSFKKAGVSIVDHHTAAKQFKQFEEREKGQGRKLTGTWSWLIPPMSSAATHIFHKDYEDEIMKPN…
A0A5B7H322 7-102 MGLDTSTNESLWKDEVNVEVNKAVLHSFQAAGVTLVDHHTASQSFIQFLANEQRDRGGCPADWVWIVPPISGSLTPVFHQEMSLYYL…
F7DLC7 377-491 None
A0A2C9JBG8 1-97 None
A0A2C9K406 255-371 None
A0A6P4EAF3 83-206 None
A0A352AP46 578-686 None
A0A1T3NPD6 289-382 None
A0A7R8XD72 98-192 None
A0A1S3IG29 247-341 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.