DPCstruct | MC44729

Metacluster Properties and Pfam Annotations

Number of structural domains115
Mean domain length (aa)192 ± 27 aa
Standard deviation of domain lengths27.40
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score68.22
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)28.03
Pfam Score89.49
Assigned Pfam label(s) PF00010- PF07527

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A226EKW0 1-191 MAPLTEISRSFGQQSPAEPISRTMQYRKITKPLLERQRRARMNRCLDELKEIMVSSENMTDKFSKSIEKADVLELSLKYIQTLQQQH…
A0A1V4K422 1-136 MTAAASASSTHKLASTKEERKLRKPLIERKRRERINNCLDQLKETVVGAFHLDQSKLEKADILEMTVKHLQNIQSSKMMADSKVGLE…
E9GEU4 32-212 None
A0A2B4SKR2 1-205 None
A0A182FTU2 4-219 None
T1DPF5 12-210 None
A0A7R8XFW8 2-226 None
A0A034V0E6 1-169 None
A0A671U2N0 21-169 None
H3BCL5 3-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.