DPCstruct | MC447

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)89 ± 8 aa
Standard deviation of domain lengths7.65
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score83.68
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)31.68
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A355D9J5 1-83 MNNEQKEKIKQMRKQGIGYKQIANEIGLSRDSVRGYCKREWDISHNKSYDLNCSYCGKEFKSLGVKHLKYCSRNCYIKDRFWR
A0A1Y3T118 5-97 MTEQQLEQIAALRKENYPYSFIGRELGLSPNTVKSICQRKGFAASGARKTKAEKQNAPLCRYCHKPLPETKRRGALFCSDYCRTKWY…
A0A3R6JJT5 1-85 None
A0A1M4X7W2 1-97 None
A0A1Y3WFJ3 1-93 None
R5BRE0 1-75 None
A0A1M6L245 1-93 None
A0A1V5GRC5 1-103 None
A0A373Q0Q3 1-95 None
R7GUV1 1-78 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.