DPCstruct | MC4469

Metacluster Properties and Pfam Annotations

Number of structural domains920
Mean domain length (aa)145 ± 32 aa
Standard deviation of domain lengths32.36
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.87
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.16
Pfam Score93.65
Assigned Pfam label(s) PF10615- CL0273- CL0063- CL0336- CL0027

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1C4I6S1 17-153 None
A0A367ZAF1 305-437 None
A0A1G5FAN8 34-168 None
J8USN7 6-135 None
A0A7W0KK00 3-133 None
A0A523SMH2 9-129 None
A0A2R6NWC1 23-147 None
A0A563ESA0 14-166 None
A0A3D3T5V4 43-170 None
E2A6T2 16-192 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.