DPCstruct | MC4469

Metacluster Properties and Pfam Annotations

Number of structural domains920
Mean domain length (aa)145 ± 32 aa
Standard deviation of domain lengths32.36
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.87
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.16
Pfam Score93.65
Assigned Pfam label(s) PF10615- CL0273- CL0063- CL0336- CL0027

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A544ZL86 10-140 None
X8FDA9 1-132 None
A0A2G6ZBV6 515-651 None
U4U7K8 45-220 None
A0A427YFS6 23-214 None
A0A2D8QV58 23-127 None
A0A4T0UWK8 95-238 None
W7TPF1 95-194 None
E2LTC1 8-186 None
A0A355AKL5 15-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.