DPCstruct | MC4469

Metacluster Properties and Pfam Annotations

Number of structural domains920
Mean domain length (aa)145 ± 32 aa
Standard deviation of domain lengths32.36
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.87
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)13.16
Pfam Score93.65
Assigned Pfam label(s) PF10615- CL0273- CL0063- CL0336- CL0027

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2U2ZDM3 8-100 None
A0A1K1P3S3 189-316 None
A0A1K1PGC6 11-155 None
A0A2W5XM75 9-131 None
A0A538D377 80-231 None
A0A344L0Y7 2-112 None
A0A3C0KWU0 22-139 None
A0A2B7GME4 9-147 None
A0A5M3XV81 281-403 None
M3J1X6 222-423 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.