DPCstruct | MC44652

Metacluster Properties and Pfam Annotations

Number of structural domains75
Mean domain length (aa)411 ± 100 aa
Standard deviation of domain lengths99.56
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score77.24
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)14.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V1DL12 67-438 ENSPRGAHQTAYLTPSHSSDPRALNTASQVAEAISPYESALWAKPLRMQMKWITRQHVVLSVRYAALSEDSPYISLKCSHFEPEDSD…
A0A2T2NEL5 518-956 ERQPKQKVSRRKGALQPQTREKASRMRKGGNTCVRCRFYKAGCDEGEPCQKCLKVANNARSFREPCSRDRIEDASLVRRCNGRFNQE…
W9NCX1 48-432 None
A0A2J6TTA7 15-351 None
A0A094KMV6 47-528 None
A0A507BIQ1 99-533 None
A0A4Z0Z122 38-343 None
G0RRG1 2-465 None
A0A420PFC6 5-321 None
A0A6A6SI52 611-1037 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.