DPCstruct | MC44632

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)176 ± 22 aa
Standard deviation of domain lengths22.19
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.46
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)24.82
Pfam Score83.33
Assigned Pfam label(s) CL0123- CL0142

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X9CEZ4 2-166 VLAFMVGPPATAYLITNDLRKMLILSPIFGILASISGYWIAVSLDVTIAGTMATMVGIIFTLVFVFLPDRGLIANSKREKTQKYDFA…
A0A2E1AKR4 305-494 VVAFFIIPPAAAYLLTDRLSVMLVISAVIGSLGAFFGYDLARGHFLGIIEMDSVLALINRVFGLQLLEQWDSSISASMVLMIFIFFI…
A0A7W0GA54 134-306 None
A0A6B1E6W3 51-273 None
A0A7C6W526 22-197 None
A0A831XUM6 98-306 None
A0A7V5Q0D8 146-334 None
A0A511R771 201-377 None
A0A1H0IW95 1-166 None
A0A353ZEW3 236-415 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.