DPCstruct | MC44616

Metacluster Properties and Pfam Annotations

Number of structural domains921
Mean domain length (aa)153 ± 28 aa
Standard deviation of domain lengths28.32
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.56
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)15.31
Pfam Score93.51
Assigned Pfam label(s) PF17969- CL0187- CL0508- CL0244- PF18058

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q6B573 23-183 None
A0A6I3KNQ5 599-824 None
A0A7K0A6C8 271-384 None
R9CDK2 107-329 None
A0A1J5KMI5 139-306 None
A0A2W6Y8W5 78-231 None
A0A3C1YIH6 241-384 None
A0A0F4KY88 219-385 None
A0A7C4AT09 43-233 None
A0A7T7F3S3 427-583 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.