DPCstruct | MC44616

Metacluster Properties and Pfam Annotations

Number of structural domains921
Mean domain length (aa)153 ± 28 aa
Standard deviation of domain lengths28.32
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score88.56
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)15.31
Pfam Score93.51
Assigned Pfam label(s) PF17969- CL0187- CL0508- CL0244- PF18058

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A151ECL1 64-222 ILEILTALNLNQGEYVFIINKEEQKAQLYKREYVLIDETRVSTGRNPGEKQRLGDNKTPSGVFEVTSLYDSTNWRFNGELAYGPKAV…
A0A0U0QP44 150-279 GDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVH…
A0A4V6PJ58 136-277 None
A0A1X1Q5K6 52-195 None
A0A1W9JP37 282-466 None
A0A417CAH7 397-585 None
A0A6M0ETD4 14-143 None
A0A416P490 469-602 None
A0A370XCJ4 21-177 None
A0A1Z8MSU6 176-362 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.