DPCstruct | MC4461

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)145 ± 13 aa
Standard deviation of domain lengths12.59
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score84.69
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)46.53
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W4CRM8 19-161 VVVPTPAAADVDVYTTEGTHNVNGRLWRTDCSMYSTTVERCRTEIQATTVTFSGSRYVEQRGWVFNNLTYKSSPRASWSFMNPLVTP…
A0A7W4CU26 2-137 YTTPGNHLVNGRYWKTACDKYSDTVVRCRTEIWTTKVATVQGQHVLHNGWVFNNLTYLPSGRDQWTGNPLAAGGKPGGTRTWTATDG…
A0A1M6CMF7 410-556 None
A0A1M6KNR8 1-119 None
A0A1M6N3N0 12-164 None
A0A553JX18 318-451 None
A0A553JX66 1-116 None
A0A553K654 313-481 None
A0A553K048 301-458 None
A0A553K1S8 8-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.