DPCstruct | MC4460

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)122 ± 17 aa
Standard deviation of domain lengths17.26
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score77.87
Mean fraction of residues predicted as intrinsically disordered0.55
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)29.79
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2YBG0 2-99 PRVTAFLREQQVEAGPASERYMVVTQARLPEGAPLQVPDSITFRQLHHIDTQQAAVDAAMTEEQLQRACEYRVVRIKLHGAVVPVQV…
W2QUD5 15-120 LPLVVDFLRSRKVSAGPATTLYMATTQARHPSDVPLEVPTSSTFQQLHEAYPTIWIVLHKVEAPIPVNIGDLRRILGLPDWNLRLPF…
D0N6I5 2-111 None
A0A6G0RPW1 1-99 None
A0A6G0RYY6 15-145 None
A0A6G0RBD9 7-136 None
A0A0W8CJV2 26-150 None
A0A6A3RYC7 52-187 None
A0A6A3QSR3 160-280 None
W2XEL4 14-117 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.