DPCstruct | MC446

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)67 ± 6 aa
Standard deviation of domain lengths6.35
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score80.97
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)35.19
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R5E241 9-76 MKQYKVIHIIEPDFGCEGLPDGSVRMDQVILQDGSGVRITVEVADAYLYEQQIDEGDVVIRTEKGICK
A0A1Y3SXA3 2-69 QEKYKVIEIFERDYGCEERAEGQTDMVQVRLCSESGKERVIETEDAALYREEITEGTEVFLIDGKLKR
A0A1Y3WGQ8 2-68 None
A0A1M6JUI3 1-58 None
A0A3D4XZC1 1-61 None
A0A416PL19 2-68 None
A0A3D2I579 32-108 None
R7QVC4 194-266 None
E0RWU7 79-138 None
A0A7G9B6E3 4-74 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.