DPCstruct | MC44536

Metacluster Properties and Pfam Annotations

Number of structural domains122
Mean domain length (aa)192 ± 26 aa
Standard deviation of domain lengths26.44
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.31
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)17.49
Pfam Score97.62
Assigned Pfam label(s) CL0436- CL0036- CL0255

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A359LRC8 12-192 QATGPVLKQQVLSASEQAQRILAEASAERERVRAEAFEAGFRAGLAQWETAIAAAQRSVHAFIEESRPSLLKLAVRIAEKILGEEVR…
A0A0K1JVP5 194-402 AARETALARREEEVSALRARLEKQEAELAAARRELDGQAAQRLADAEQRGQAQGQERALQEAKEAAQKAQEAAAQRLAALDAAIAAF…
A0A443ZGM4 2-180 None
A0L4A5 35-236 None
A0A212CD21 1-131 None
A0A6A4JZ25 11-234 None
A0A2X2CSX6 6-180 None
A0A7K4HFD5 3-158 None
A0A5J4YYV0 7-217 None
A0A2K1J527 7-174 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.