DPCstruct | MC4452

Metacluster Properties and Pfam Annotations

Number of structural domains16017
Mean domain length (aa)309 ± 95 aa
Standard deviation of domain lengths95.33
Length coefficient of variation0.31
Mean AlphaFold2 pLDDT confidence score83.48
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.89
Pfam Score67.82
Assigned Pfam label(s) PF12309- PF08492- PF18972- CL0003- CL0144

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1W0E9E3 22-381 None
A0A1W0E9E1 15-369 None
A0A0F9MJ12 378-786 None
A0A0R3MNI2 462-882 None
A0A7X6HSA1 266-517 None
A0A1I0DER9 11-234 None
A0A1I0KA87 185-457 None
A0A0T5NWL1 137-406 None
A0A0L0P5H9 14-349 None
A0A135ZZR1 375-682 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.