DPCstruct | MC4452

Metacluster Properties and Pfam Annotations

Number of structural domains16017
Mean domain length (aa)309 ± 95 aa
Standard deviation of domain lengths95.33
Length coefficient of variation0.31
Mean AlphaFold2 pLDDT confidence score83.48
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.89
Pfam Score67.82
Assigned Pfam label(s) PF12309- PF08492- PF18972- CL0003- CL0144

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E3S345 563-749 None
A0A4V1MBB2 231-462 None
A0A661WTI2 702-919 None
A0A6M1YMZ3 4-382 None
A0A5C7RQK1 90-426 None
A0A5C7S1Q5 94-249 None
A0A7C6RWP1 3-199 None
A0A6V8LNK8 272-639 None
A0A842Z922 314-601 None
A0A842ZGI9 1-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.