DPCstruct | MC4452

Metacluster Properties and Pfam Annotations

Number of structural domains16017
Mean domain length (aa)309 ± 95 aa
Standard deviation of domain lengths95.33
Length coefficient of variation0.31
Mean AlphaFold2 pLDDT confidence score83.48
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.89
Pfam Score67.82
Assigned Pfam label(s) PF12309- PF08492- PF18972- CL0003- CL0144

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A554A3L8 20-314 None
A0A7Y4SU90 644-839 None
A0A7Y3XIZ4 26-183 None
A0A7Y3XGF7 79-388 None
A0A812X1L2 386-842 None
A0A812Y5E0 207-563 None
A0A496CUH0 325-674 None
E9HRJ2 5-322 None
A0A2V1P0F8 15-245 None
A0A2P5DDL9 8-442 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.