DPCstruct | MC4452

Metacluster Properties and Pfam Annotations

Number of structural domains16017
Mean domain length (aa)309 ± 95 aa
Standard deviation of domain lengths95.33
Length coefficient of variation0.31
Mean AlphaFold2 pLDDT confidence score83.48
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.89
Pfam Score67.82
Assigned Pfam label(s) PF12309- PF08492- PF18972- CL0003- CL0144

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5N6E9M7 4-437 None
A0A522XAA4 181-418 None
A0A6B1E1Y4 187-336 None
A0A6L3EXS8 299-619 None
A0A6L3F0C4 128-290 None
A0A6J1ECZ4 61-513 None
A0A0D9Y1T0 353-679 None
A5GQ15 2-245 None
A5GUR3 19-217 None
A0A538Q0F1 15-307 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.