DPCstruct | MC4452

Metacluster Properties and Pfam Annotations

Number of structural domains16017
Mean domain length (aa)309 ± 95 aa
Standard deviation of domain lengths95.33
Length coefficient of variation0.31
Mean AlphaFold2 pLDDT confidence score83.48
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.34
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.89
Pfam Score67.82
Assigned Pfam label(s) PF12309- PF08492- PF18972- CL0003- CL0144

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3C0A2Z3 145-463 None
A0A3C0A3S9 81-418 None
A0A3C1EP43 48-408 None
A0A3C1ESA8 186-456 None
A0A3E1RCZ6 156-373 None
A0A4Q5XK37 148-451 None
A0A4Q5XV48 319-654 None
A0A4V1V418 196-375 None
A0A520W6J9 2-122 None
A0A520W9L0 278-551 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.